Deflazacort side effects
When looking at Deflazacort side effects, the unwanted reactions that can appear while taking the corticosteroid deflazacort. Also known as Deflazacort adverse reactions, it is a type of corticosteroid, a class of drugs that mimic natural hormones. One of the major concerns linked to this class is adrenal suppression, where the body’s own cortisol production drops.
Key considerations for patients and caregivers
Deflazacort can cause a range of noticeable effects. The most common include increased appetite, weight gain, and a tendency to retain fluid. Many users also report mood swings or sleep disturbances. A less obvious but serious issue is bone density loss; long‑term use can weaken the skeleton, raising fracture risk. Skin thinning and easy bruising often show up early, signaling that the drug is affecting collagen production.
Because deflazacort interferes with hormone balance, doctors usually recommend regular blood work. Monitoring blood sugar helps catch steroid‑induced hyperglycemia, while liver function tests spot any enzyme elevation. Blood pressure checks are routine too, since sodium retention can push numbers higher. Adjusting the dose based on these measurements keeps the treatment safe and effective.
Drug interactions matter a lot. NSAIDs taken together can increase stomach ulcer risk, while certain antidiabetic medications may need dose tweaks to offset blood‑sugar spikes. Antibiotics like rifampin can speed up deflazacort metabolism, reducing its effectiveness. Always list current medicines to your prescriber; a quick review can prevent unwanted side effects.
Special populations need extra attention. Children often receive deflazacort for muscular dystrophy, and their growth plates can be sensitive to steroid exposure. In the elderly, the risk of osteoporosis and cataracts rises sharply, so calcium and vitamin D supplementation become essential. Pregnant or nursing individuals should discuss alternatives, as steroids can cross the placenta.
Managing side effects starts with lifestyle tweaks. A diet rich in calcium, vitamin D, and protein supports bone health. Weight‑bearing exercise, even short daily walks, helps maintain muscle mass and bone strength. If you notice mood changes, talk to a therapist or consider short‑term anti‑anxiety meds under supervision. For fluid retention, reducing salt intake and staying hydrated can make a noticeable difference.
Below you’ll find a curated collection of articles that dive deeper into each of these topics. From detailed comparisons of deflazacort with other steroids to practical guides on monitoring adrenal function, the posts are designed to give you actionable insights and help you navigate the medication safely.

Deflazacort vs Other Corticosteroids: Detailed Comparison of Alternatives
Oct, 7 2025